Pork was able to reduce the level of the patient’s kidney molecule creatinine, a key indicator of kidney health, which had become extremely high in the patient before the transplant.
Pig Kidney Transplant To Human
In America, for the first time in the world, a pig kidney has been transplanted into a human body. This feat was accomplished by surgeons at NYU Langone Health Medical Center in New York City. The great thing is that the pig’s kidney is also working successfully in the human body. With this successful transplant, the shortage of human organs can be overcome in the coming days. To overcome the lack of organs, research was being done on pigs for a long time. A sugar present in pig cells is not accepted by the human body. For this reason, all the earlier attempts were unsuccessful, so this time the doctors used pigs with special modified genes. In this, some genetic changes were made to eliminate that sugar present in the pig’s cell and to avoid the attack of the immune system.
An American medical team has succeeded in temporarily transplanting a pig’s kidney to a person. The surgeon who led the procedure called it a potential miracle. The surgery, performed on September 25, involved a genetically modified donor animal and a brain-dead patient whose family had allowed a two-day experiment for the betterment of science. “It did what it was supposed to do, remove waste and make urine,” Robert Montgomery, director of the Transplant Institute at New York University Langone, told AFP in an interview.
Pig’s Kidney in Human
In this critical condition, the pig was able to reduce the level of the patient’s kidney molecule creatine, a key indicator of kidney health, which had become extremely high in the patient before the transplant. Montgomery, along with several of his colleagues, performed the surgery over the course of about two hours.
University of Birmingham surgeon Hynek Mergental said that this is a significant achievement in the xenotransplantation field.
Montgomery said the patient wanted to donate his own organs, but his family was initially disappointed when they were told their loved one’s organs were not suitable for donation. “We felt relieved, it was yet another donation opportunity,” he said. The patient was taken off the ventilator and died after 54 hours of testing.
The pigs from which the kidneys were taken belonged to a group that had been genetically modified to remove the sugar-causing gene that promoted a stronger immune response.
Creatinine level in the body is also normal
“It’s still a question of what will happen three weeks, three months, three years from now,” Montgomery said. Montgomery plans to submit the findings to a scientific journal next month. He says that the clinical trial can be done in about a year or two. This news has been cautiously welcomed by many other experts. He said that he would like to see the peer-reviewed data before drawing firm conclusions.
“This news is a significant scientific achievement in the xenotransplantation field,” Hynek Mergental, a surgeon at the University of Birmingham in the UK, said in a statement. He said that if confirmed, it would be a big step in the field of organ transplant, which can solve the acute shortage of organs that can be given to a person.
Montgomery also said that the creatinine level in the patient’s body was abnormal before. Usually, when a patient’s kidney does not work properly, then his creatinine level becomes high or low. Surprisingly, after the transplantation of this kidney, the level of creatinine in that patient’s body returned to normal. This genetically modified swine was developed by United Therapeutics Corp’s Revivicor unit.